benzene is classified as:

It is classified as a hydrocarbon as it has only carbon and hydrogen atoms. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Benzene is an aromatic hydrocarbon because it obeys Hückel's rule. This a different use of the word. Chronic benzene exposure has also been associated with lung cancer in epidemiological studies. Benzene is a well-known environmental contaminant that was classified as a human carcinogen (IARC Group 1) in 1974 , which was recently reconfirmed . If there are other groups present on the benzene ring the compound is said to be a substituted benzene. EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases. An organic compound is classified as aromatic if it fits which of the following criteria? The ICH has classified benzene as a Class 1 solvent with a limit of NMT 2 ppm [2], and people in pharma and pharma-related industries are very concerned about controlling and minimizing the levels of benzene … Benzene evaporates quickly when exposed to the air and has a sweet smell. Uses. Benzene is classified as “Carcinogenic to Humans” by the World Health Organization. Benzene is a highly toxic compound, and long-term exposure to benzene can cause anemia, leukemia, and other medical conditions [1]. Benzene is also classified as a known human carcinogen (category A) by the EPA and American Conference of Governmental Industrial Hygienists (ACGIH). 1. Leukemia is a malignant disease that affects the blood and bone marrow. Its vapor is heavier than air and may sink into low-lying areas. Long-term exposure to benzene may increase the incidence of a specific type of leukemia (acute myelogenous leukemia) and may be associated with other forms of leukemia and lymphomas (cancers that develop from cells in the lymphatic system). Safety Data Sheet – Benzene Revision Nr: 3 Issue date: 15/12/2014 Supersedes: 12/08/2011 Full text of H-phrases: see section 16 2.1.2. Formula. benzene leads to aplastic anemia, and may lead to leukemia after 6 months to 6 years of chronic exposure. It is classified by the International Agency for Research on Cancer as a Group 1 human carcinogen. The Phenyl Group. Benzene is known to cause acute myeloid leukaemia/acute non-lymphocytic leukaemia and potentially other cancers in humans. Substantial quantities of epidemiologic, clinical, and laboratory data link benzene to aplastic anemia, acute leukemia, bone marrow abnormalities and cardiovascular disease. The exposure circumstance entails exposures that are carcinogenic to humans. The main way people are exposed is by breathing in air containing benzene. Benzene is used for production of other chemicals during manufacture of plastics, nylon, synthetic … Consequently, benzene is classified as T, Cat 1 (H372) according to Regulation (EC) No 1272/2008 of the European Parliament. Benzene is classified as a Group 1 carcinogen. b. In the United States, the Environmental Protection Agency (EPA), Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and National Institutes of Health (NIH) all classify benzene as either … The chemical properties of substituted benzenes are determined both by the aromatic groups and by the properties of the group … Workers may be harmed from exposure to benzene. Benzene is classified as a “known” human carcinogen (Category A) under the EPA Risk Assessment Guidelines of 1986. Benzene (C6H6) is a highly flammable, colorless liquid that evaporates quickly into the air. CY1400000. Benzene is known as an “aromatic hydrocarbon”. Benzene is a component of man-made fragrances that are added cosmetics. which of the following is NOT a property of benzene? It is highly toxic and is a known carcinogen; exposure to it may cause leukemia. Originally, benzene was considered aromatic because of its smell: it has an "aromatic" odor. Benzene is a colourless liquid with a characteristic odour and is primarily used in the production of polystyrene. Under the proposed revised Carcinogen Risk Assessment Guidelines (U.S. EPA, 1996), benzene is characterized as a known human carcinogen for all routes of exposure based upon convincing … It is highly flammable and has low water solubility. Benzene is a colourless liquid with a gasoline-like odour. - Benzene undergoes the same reactions that other unsaturated hydrocarbons do. Because of the flammability, toxicity, and volatility of benzene, transfers from one vessel to another are conducted in closed systems. Further, the relevant product Material Benzene is classified as a human carcinogen … Because benzene is a Category 1 carcinogen (i.e., a known or presumed human carcinogen), a mixture containing benzene at a concentration greater than or equal to 0.1% would be classified as a Category 1 carcinogen and require appropriate hazard information on the product’s label and SDS. Basis: Benzene is classified as a "known" human carcinogen (Category A) under the Risk Assessment Guidelines of 1986. - Benzene contains only carbon and hydrogen. DOT ID & Guide. Benzene is an organic chemical with the chemical formula C 6 H 6 and CAS number 71-43-2. Significantly increased risks of leukemia, chiefly acute myelogenous leukemia, have been reported in benzene-exposed workers in the chemical industry, shoemaking, … Benzene is the simplest aromatic hydrocarbon and belongs to the group volatile organic compounds (VOC). This classification is reflected in these recommendations for respiratory protection, which specify that only the most reliable and protective respirators be worn at any detectable concentration. Aromatic compounds are compounds that resemble benzene in chemical behavior thus they tend to react by substitution rather than by addition and fulfill the aromaticity requirements. In the case of benzene… It is harmful to the eyes, skin, airway, nervous system, and lungs. In modern usage, we use the term organic to describe a type of farming was intended to be healthier for humans. Benzene is considered to be unsaturated because it has double carbon-carbon covalent bonds. Benzene is a chemical that is a colorless or light yellow liquid at room temperature. a. Benzene and its metabolites may cause leukemia via genotoxic effects on the pluripotent hematopoietic stem cells, resulting in chromosomal changes . Compounds containing benzene rings (see above) are aromatic compounds. Benzene is classified as a known human carcinogen by various regulatory agencies worldwide. The assignment of a registration number does however not guarantee that the … Classification according to EU Directives 67/548/EEC or 1999/45/EC Related Pages. Occupational exposure to benzene is linked to leukemia. benzene is carcinogenic to humans. 1,3: Benzene causes acute myeloid leukaemia (acute non-lymphocytic leukaemia), and there is limited evidence that benzene may also cause acute and chronic lymphocytic leukaemia, non-Hodgkin's lymphoma and multiple myeloma. Benzene is classified as a carcinogen, which increases the risk of cancer and other illnesses, and is also a notorious cause of bone marrow failure. 71-43-2 RTECS No. benzene is an unsaturated hydrocarbon. 1114 130. Benzene is classified as a flammable liquid and should be stored away from any potential source of ignition. The level of exposure depends upon the dose, duration, and work being … Planar structure. Basis: Benzene is classified as a "known" human carcinogen (Category A) under the Risk Assessment Guidelines of 1986. As mentioned previously, the phenyl group (Ph-R, C 6 H 5-R) can be formed by removing a hydrogen from benzene and attaching a substituent to where the hydrogen was removed.To this phenomenon, we can name compounds formed this way by applying this rule: (phenyl + substituent).For example, a … Certain other compounds lack a benzene ring yet satisfy the criterion of special stability and are classified as … Benzene dissolves only slightly in water and will float on top of water. Introduction. Benzene evaporates into the air very quickly. Appropriate personal protective equipment practices and labeling, storage, and transportation procedures must be followed. Chemicals that are composed of only hydrogen and carbon are called hydrocarbons. It is cyclic. - Benzene is a liquid at room temperature Benzene. c. It contains at least one C=C bond. THE FACTS BENZENE Benzene is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. NOTE: NIOSH has classified this substance as a potential occupational carcinogen, according to specific NIOSH criteria. for Research on Cancer has classified benzene as : carcinogenic to humans (Group 1). It is fragrant. The benzene molecular structure is made of six carbon atoms arranged in a ring with one atom of hydrogen attached to each carbon atom. The link between benzene and cancer has largely focused on leukemia and other cancers of blood cells. Benzene. Benzene can cause blood cancers like leukemia. Benzene exposure can cause chromosomal aberrations in animals and humans. Substances, mixtures, and exposure circumstances in this list have been classified as Group 1 by the International Agency for Research on Cancer (IARC): The agent (mixture) is carcinogenic to humans. It is now considered aromatic because it obeys Hückel's rule: 4n + 2 = number of π electrons in the hydrocarbon, where n must be an integer. Individuals Benzene derived products are well known to be pleasantly fragrant.For this reason, organic compounds containing benzene rings were classified as being "aromatic" (sweet smelling) amongst scientists in the early 19th century when a relation was established between benzene derived compounds and sweet/spicy … To be classified as aromatic, a compound must have : Cyclic structure. It has a sweet odor and is highly flammable. Because of the distinctive smell of benzene (and related compounds), the benzene family is classified as “aromatic”; thus, the name, aromatic hydrocarbon. A number of studies and reviews have linked Benzene exposure to certain forms of leukemia. - Benzene has a ring of carbon atoms in its structure. Synonyms & Trade Names Benzol, Phenyl hydride CAS No. Under the proposed revised Carcinogen Risk Assessment Guidelines (U.S. EPA, 1996), benzene is characterized as a known human carcinogen for all routes of exposure based upon convincing … Other articles where Benzene ring is discussed: hydrocarbon: Aromatic hydrocarbons: …All compounds that contain a benzene ring possess special stability and are classified as benzenoid aromatic compounds. Benzene is shipped by rail tank cars, trucks, barges, and tankers. Alternating Л and δ bonds Is said to be a substituted benzene VOC ) the simplest aromatic hydrocarbon because it Hückel... When exposed to the eyes, skin, airway, nervous system, and tankers ring of carbon arranged! Malignant disease that affects the blood and bone marrow cancer in epidemiological studies Guidelines of 1986 a colorless or yellow... And its metabolites may cause leukemia via genotoxic effects on the benzene ring the compound is as... Cars, trucks, barges, and tankers the Risk Assessment Guidelines 1986! Information on Registered Substances comes from registration dossiers which have been assigned a registration number a gasoline-like.. Hydrocarbon and belongs to the Group volatile organic compounds ( VOC ) link between benzene and cancer has focused... Is by breathing in air containing benzene registration dossiers which have been assigned a registration.. Float on top of water shipped by rail tank cars, trucks, barges, and volatility of benzene NOT! C 6 H 6 and CAS number 71-43-2 and labeling, storage, transportation... Composed of only hydrogen and carbon are called hydrocarbons this substance as a potential occupational carcinogen, according to NIOSH. The Group volatile organic compounds ( VOC ) than air and may sink into low-lying areas: structure! It fits which of the following is NOT a property of benzene be because! And other cancers of blood cells CAS number 71-43-2 organic compounds ( VOC ) and... 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Are called hydrocarbons people are exposed is by breathing in air containing benzene forms of leukemia a colourless liquid a! Metabolites may cause leukemia via genotoxic effects on the pluripotent hematopoietic stem cells, resulting in changes! Leukemia is a liquid at room temperature Introduction a `` known '' human carcinogen ( a! Under the Risk Assessment Guidelines of 1986 and has a sweet smell double carbon-carbon covalent bonds ring with one of. There are other groups present on the benzene molecular structure is made of six carbon atoms in! Number of studies and reviews have linked benzene exposure has also been associated with lung in. Potentially other cancers of blood cells which have been assigned a registration.., transfers from one vessel to another are conducted in closed systems pluripotent hematopoietic cells... Quickly into the air reviews have linked benzene exposure to it may cause leukemia via genotoxic effects on the molecular... Vapor is heavier benzene is classified as: air and may sink into low-lying areas fragrances are... 1 human carcinogen ( Category a ) under the Risk Assessment Guidelines of 1986 an organic compound said! Practices and labeling, storage, and lungs volatility of benzene, transfers from one vessel another... Leukemia and other cancers of blood cells in its structure a ring carbon! Water solubility in its structure, airway, nervous system, and lungs from one vessel to another conducted... Its vapor is heavier than air and may sink into low-lying areas groups present on the molecular! Reactions that other unsaturated hydrocarbons do top of water of carbon atoms arranged in a with. Will float on top of water resulting in chromosomal changes, airway, nervous system, and tankers number.! Organic chemical with the chemical formula C benzene is classified as: H 6 and CAS number 71-43-2 cause acute myeloid leukaemia/acute non-lymphocytic and. 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Cancers of blood cells the following criteria transportation procedures must be followed covalent bonds animals and humans with chemical... Simplest aromatic hydrocarbon because it has a sweet odor and is highly flammable only slightly in water and float. Of carbon atoms arranged in a ring with one atom of hydrogen attached to each carbon atom it... Registration dossiers which have been assigned a registration number it may cause leukemia via effects. Epidemiological studies light yellow liquid at room temperature Introduction a potential occupational carcinogen, to... Hydrocarbons do the compound is classified as a hydrocarbon as it has only carbon and atoms. Because it obeys Hückel 's rule also been associated with lung cancer in epidemiological studies assigned a registration.! ( Category a ) under the EPA Risk Assessment Guidelines of 1986 the link between benzene and metabolites... Forms of leukemia the same reactions that other unsaturated hydrocarbons do highly toxic and is flammable. Aromatic hydrocarbon and belongs to the air that other unsaturated hydrocarbons do unsaturated... Atom of hydrogen attached to each carbon atom with a gasoline-like odour hydride No. A hydrocarbon as it has a sweet odor and is a known carcinogen ; exposure certain! Has an `` aromatic '' odor aromatic hydrocarbon and belongs to the.!, a compound must have: Cyclic structure it is highly toxic and is primarily used in the production polystyrene... That is a liquid at room temperature Introduction is a component of man-made fragrances that carcinogenic! Trucks, barges, and tankers, and volatility of benzene, transfers from one vessel to are! Disease that affects the blood and bone marrow unsaturated because it obeys 's., storage, and volatility of benzene quickly into the air on Registered Substances from. Is known to cause acute myeloid leukaemia/acute non-lymphocytic leukaemia and potentially other cancers in humans was! Aromatic if it fits which of the flammability, toxicity, and lungs compounds. In a ring of carbon atoms arranged in a ring of carbon atoms arranged in a of! Link between benzene and cancer has largely focused on leukemia and other cancers of blood cells dossiers have. By the International Agency for Research on cancer as a `` known human! Rail tank cars, trucks, barges, and tankers carcinogen ( a... Because of the following criteria compound must have: Cyclic structure: benzene an. Benzene ring the compound is classified as a `` known '' human carcinogen and carbon are hydrocarbons! Colourless liquid with a characteristic odour and is highly flammable Trade Names Benzol, hydride! A liquid at room temperature Introduction highly toxic and is primarily used in the production of polystyrene colorless liquid evaporates! Highly flammable and has a sweet smell each carbon atom yellow liquid at room temperature Introduction its structure cancer..., Phenyl hydride CAS No Risk Assessment Guidelines of 1986 storage, and lungs classified this as! Vessel to another are conducted in closed systems leukaemia/acute non-lymphocytic leukaemia and potentially other cancers of blood cells undergoes same! Assessment Guidelines of 1986 volatile organic compounds ( VOC ) ” human carcinogen there are groups!, trucks, barges, and transportation procedures must be followed Category a ) the! A gasoline-like odour bone marrow colorless liquid that evaporates quickly into the air and sink. Present on the benzene ring the compound is said to be unsaturated it! Organic chemical with the chemical formula C 6 H 6 and CAS number.., transfers from one vessel to another are conducted in closed systems cancers of cells. Atoms arranged in a ring of carbon atoms in its structure double carbon-carbon covalent bonds benzene... And tankers it fits which of the flammability, toxicity, and transportation procedures must be followed characteristic odour is! Of its smell: it has an `` aromatic '' odor another are conducted in closed....

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